| 23 Jun 2022 | Derbyshire | Nottinghamshire | Trent Bridge | 0 (1) | 0/22 (1.0) | Nottinghamshire won by 94 runs |
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| 21 Jun 2022 | Derbyshire | Northamptonshire | County Ground | – | 1/24 (2.0) | Derbyshire won by 6 wickets |
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| 19 Jun 2022 | Derbyshire | Birmingham Bears | Edgbaston | – | 3/25 (3.0) | Derbyshire won by 7 wickets |
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| 18 Jun 2022 | Derbyshire | Yorkshire | Queen's Park | – | 0/17 (1.0) | Derbyshire won by 6 wickets (DLS) |
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| 10 Jun 2022 | Derbyshire | Worcestershire | County Ground, New Road | – | – | Derbyshire won by 39 runs |
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| 9 Jun 2022 | Derbyshire | Leicestershire | County Ground | – | 0/19 (2.0) | Derbyshire won by 6 wickets |
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| 7 Jun 2022 | Derbyshire | Northamptonshire | County Ground | 2 (4) | 1/18 (2.1) | Northamptonshire won by 5 wickets |
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| 3 Jun 2022 | Derbyshire | Nottinghamshire | County Ground | 2 (2) | 0/41 (2.1) | Nottinghamshire won by 7 wickets |
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| 1 Jun 2022 | Derbyshire | Lancashire | Old Trafford | – | 1/56 (4.0) | Lancashire won by 17 runs |
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| 31 May 2022 | Derbyshire | Yorkshire | Headingley | – | 0/23 (2.0) | Derbyshire won by 9 wickets |
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